G(M2) Activator Protein

An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT.

Year introduced: 2005(1983)

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Tree Number(s): D08.211.790.249

MeSH Unique ID: D049289

Entry Terms:

• GM(2) Activating Protein
• GM2 Activator Protein
• Activator Protein, GM2
• Hexosaminidase Activator

Previous Indexing:

• Proteins (1983-2004)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Coenzymes
Sphingolipid Activator Proteins
G(M2) Activator Protein