Succinate-Semialdehyde Dehydrogenase
An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).
Year introduced: 2006(1980)
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Subheadings:
Tree Number(s): D08.811.682.657.163.843
MeSH Unique ID: D050644
Registry Number: EC 1.2.1.24
Entry Terms:
- Dehydrogenase, Succinate-Semialdehyde
- NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase
- Succinate Semialdehyde Dehydrogenase
- Dehydrogenase, Succinate Semialdehyde
- Semialdehyde Dehydrogenase, Succinate
- Succinic Semialdehyde Dehydrogenase
- Dehydrogenase, Succinic Semialdehyde
- Semialdehyde Dehydrogenase, Succinic