E2F Transcription Factors

A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.

Year introduced: 2006(1991)

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Tree Number(s): D12.776.930.211

MeSH Unique ID: D050684

Entry Terms:

• Transcription Factors, E2F
• Transcription Factor E2F
• E2F, Transcription Factor
• E2F Proteins
• E2F Transcription Factor
• Factor, E2F Transcription
• Transcription Factor, E2F

Previous Indexing:

• Cell Cycle Proteins (1991-2005)
• DNA-Binding Proteins (1991-2005)
• Transcription Factors (1991-2005)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
E2F Transcription Factors
E2F1 Transcription Factor
E2F2 Transcription Factor
E2F3 Transcription Factor
E2F4 Transcription Factor
E2F5 Transcription Factor
E2F6 Transcription Factor
E2F7 Transcription Factor