Complement C1 Inhibitor Protein
An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.
Year introduced: 2006
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Tree Number(s): D09.400.430.780, D12.644.861.140.500, D12.776.124.486.274.920.250.500, D12.776.395.320, D12.776.872.140.500
MeSH Unique ID: D050718
Entry Terms:
- C1 Esterase Inhibitor
- Esterase Inhibitor, C1
- C1-Inhibitor Protein
- C1 Inhibitor Protein
- C1-INH Protein
- C1 INH Protein
- Plasma Protease C1 Inhibitor
- Complement C1-Inhibitor Protein
- Serpin G1
- Serpin Family G Member 1
- SERPING1
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