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Complement C1 Inhibitor Protein

An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.

Year introduced: 2006

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Subheadings:

Tree Number(s): D09.400.430.780, D12.644.861.140.500, D12.776.124.486.274.920.250.500, D12.776.395.320, D12.776.872.140.500

MeSH Unique ID: D050718

Entry Terms:

  • C1 Esterase Inhibitor
  • Esterase Inhibitor, C1
  • C1-Inhibitor Protein
  • C1 Inhibitor Protein
  • C1-INH Protein
  • C1 INH Protein
  • Plasma Protease C1 Inhibitor
  • Complement C1-Inhibitor Protein
  • Serpin G1
  • Serpin Family G Member 1
  • SERPING1

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