Retinoblastoma-Like Protein p107
A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
Year introduced: 2006(1991)
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Subheadings:
Tree Number(s): D12.776.624.776.717, D12.776.660.770, D12.776.744.747
MeSH Unique ID: D050720
Entry Terms:
- p107, Retinoblastoma-Like Protein
- Retinoblastoma Like Protein p107
- Retinoblastoma-Like Protein 1
- Retinoblastoma Like Protein 1
- p107 Tumor Suppressor Protein
- RBL1 Protein