Protein Inhibitors of Activated STAT
A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.
Year introduced: 2006(1998)
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Subheadings:
Tree Number(s): D12.644.360.024.319, D12.776.157.057.124, D12.776.476.024.402
MeSH Unique ID: D050828
Entry Terms:
- PIAS Proteins
- PIAS1 Protein Inhibitor of Activated STAT
- PIAS1 Protein
- PIAS2 Protein Inhibitor of Activated STAT
- PIAS3 Protein Inhibitor of Activated STAT
- PIAS4 Protein Inhibitor of Activated STAT