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Protein Inhibitors of Activated STAT

A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.

Year introduced: 2006(1998)

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Subheadings:

Tree Number(s): D12.644.360.024.319, D12.776.157.057.124, D12.776.476.024.402

MeSH Unique ID: D050828

Entry Terms:

  • PIAS Proteins
  • PIAS1 Protein Inhibitor of Activated STAT
  • PIAS1 Protein
  • PIAS2 Protein Inhibitor of Activated STAT
  • PIAS3 Protein Inhibitor of Activated STAT
  • PIAS4 Protein Inhibitor of Activated STAT

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