Interferon-Stimulated Gene Factor 3
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
Year introduced: 2006(1990)
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Subheadings:
Tree Number(s): D12.644.360.024.303, D12.776.157.057.061, D12.776.260.513, D12.776.476.024.386, D12.776.930.354
MeSH Unique ID: D050832
Entry Terms:
- Interferon Stimulated Gene Factor 3
- ISGF3 Factor
- Transcription Factor ISGF3
- ISGF3, Transcription Factor
- IFN-Stimulated Gene Factor 3 Complex
- IFN Stimulated Gene Factor 3 Complex
- ISGF3 Transcription Factor
- Transcription Factor, ISGF3