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Wiskott-Aldrich Syndrome Protein Family

A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.

Year introduced: 2006(1999)

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Subheadings:

Tree Number(s): D05.750.078.730.912, D12.776.220.525.912

MeSH Unique ID: D051300

Entry Terms:

  • Wiskott Aldrich Syndrome Protein Family
  • WAS Protein Family
  • WASP Protein Family
  • Wiskott-Aldrich Syndrome Protein Family, Member 1
  • Wiskott Aldrich Syndrome Protein Family, Member 1
  • WAS Protein Family, Member 1
  • WASF1 Protein
  • WAVE1 Protein
  • Wiskott-Aldrich Syndrome Protein Family, Member 2
  • Wiskott Aldrich Syndrome Protein Family, Member 2
  • WAS Protein Family, Member 2
  • WASF2 Protein
  • WAVE2 Protein
  • Wiskott-Aldrich Syndrome Protein Family, Member 3
  • Wiskott Aldrich Syndrome Protein Family, Member 3
  • WAS Protein Family, Member 3
  • WASF3 Protein
  • WAVE3 Protein
  • WASP-Family Verprolin Homologous Proteins
  • WASP Family Verprolin Homologous Proteins
  • WAVE Proteins

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