Paxillin
Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.
Year introduced: 2006(1991)
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Tree Number(s): D12.644.360.024.316, D12.776.157.057.092, D12.776.476.024.397, D12.776.512.374, D12.776.744.665
MeSH Unique ID: D051419