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TNF-Related Apoptosis-Inducing Ligand

A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.

Year introduced: 2007(2005)

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Subheadings:

Tree Number(s): D12.644.276.374.750.625, D12.776.467.374.750.625, D23.529.374.750.625

MeSH Unique ID: D053221

Entry Terms:

  • Apoptosis-Inducing Ligand, TNF-Related
  • TNF Related Apoptosis Inducing Ligand
  • CD253 Antigen
  • Antigen, CD253
  • Apo-2 Ligand
  • Apo 2 Ligand
  • TRAIL Protein
  • Apo-2L Protein
  • Apo 2L Protein
  • TNF Superfamily, Member 10
  • Tumor Necrosis Factor Ligand Superfamily Member 10

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