Edar-Associated Death Domain Protein
A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein for the EDAR RECEPTOR and plays an important role in ectodermal development. It binds to edar receptor via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of edar-associated death domain protein is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA.
Year introduced: 2007(2002)
PubMed search builder options
Subheadings:
Tree Number(s): D12.644.360.024.285.100, D12.644.360.024.500.061, D12.644.360.075.421.100, D12.776.157.057.018.100, D12.776.157.057.500.061, D12.776.476.024.320.100, D12.776.476.024.500.061, D12.776.476.075.421.100
MeSH Unique ID: D053362
Entry Terms:
- Edar Associated Death Domain Protein
- Edaradd Protein