TYK2 Kinase

A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of the janus kinase family and was initially discovered as a signaling partner for the INTERFERON ALPHA-BETA RECEPTOR. The kinase has since been shown to signal from several INTERLEUKIN RECEPTORS.

Year introduced: 2007

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Tree Number(s): D08.811.913.696.620.682.725.124.650, D12.776.476.568.124.650

MeSH Unique ID: D053634

Registry Number: EC 2.7.10.2

Entry Terms:

• Kinase, TYK2
• Tyrosine Kinase 2
• Non-Receptor Tyrosine-Protein Kinase TYK2
• Non Receptor Tyrosine Protein Kinase TYK2

Previous Indexing:

• Protein-Tyrosine Kinase (1991-2006)

See Also:

• src Homology Domains

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
Phosphotransferases
Phosphotransferases (Alcohol Group Acceptor)
Protein Kinases
Protein-Tyrosine Kinases
Janus Kinases
TYK2 Kinase

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Janus Kinases
TYK2 Kinase