Syndecans
A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.
Year introduced: 2007(1989)
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Tree Number(s): D09.400.430.890.847, D09.400.430.930.350.500, D12.776.395.550.847, D12.776.395.650.350.500, D12.776.543.550.847
MeSH Unique ID: D053667
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