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Leukemia, Large Granular Lymphocytic

A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.

Year introduced: 2008

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Tree Number(s): C04.557.337.428.580.049, C15.378.508.428.580.049, C15.604.515.560.575.049, C20.683.515.528.582.049

MeSH Unique ID: D054066

Entry Terms:

  • Aggressive NK Cell Leukemia
  • Leukemia, Lymphocytic, Large Granular
  • Lymphoproliferative Disease of Granular Lymphocytes
  • LGL Leukemia
  • Leukemias, LGL
  • LGL Leukemias
  • Lymphoproliferative Disease of Large Granular Lymphocytes
  • Leukemia, LGL
  • Aggressive Natural Killer Cell Leukemia
  • Large Granular Lymphocyte Leukemia
  • Leukemia, T-Cell Large Granular Lymphocytic
  • Leukemia, T Cell Large Granular Lymphocytic
  • T-LGL Leukemia
  • Leukemias, T-LGL
  • T LGL Leukemia
  • T-LGL Leukemias
  • T-Cell Large Granular Lymphocytic Leukemia
  • T Cell Large Granular Lymphocytic Leukemia
  • Large Granular Lymphocytosis
  • Granular Lymphocytoses, Large
  • Granular Lymphocytosis, Large
  • Large Granular Lymphocytoses
  • Lymphocytoses, Large Granular
  • Lymphocytosis, Large Granular
  • Leukemia, T-LGL
  • Leukemia, T LGL
  • T-Cell Large Granular Lymphocyte Leukemia
  • T Cell Large Granular Lymphocyte Leukemia
  • Leukemia, Natural Killer Cell Large Granular Lymphocytic
  • NK-Cell Large Granular Lymphocytic Leukemia
  • NK Cell Large Granular Lymphocytic Leukemia
  • Natural Killer Cell Large Granular Lymphocytic Leukemia
  • NK-LGL Leukemia
  • Leukemias, NK-LGL
  • NK LGL Leukemia
  • NK-LGL Leukemias
  • Leukemia, NK-LGL
  • Leukemia, NK LGL

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