Growth Differentiation Factor 1
A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.
Year introduced: 2009(2005)
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Tree Number(s): D12.644.276.954.300.100, D12.644.276.954.550.100, D12.776.467.942.300.100, D12.776.467.942.550.100, D23.529.942.300.100, D23.529.942.550.100
MeSH Unique ID: D055452
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