Acid Ceramidase

A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.

Year introduced: 2009(1982)

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Tree Number(s): D08.811.277.087.250.100

MeSH Unique ID: D055573

Registry Number: EC 3.5.1.23

Previous Indexing:

• Galactosylgalactosylglucosylceramidase (1974-2008)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Hydrolases
Amidohydrolases
Ceramidases
Acid Ceramidase