Nuclear Receptor Coactivator 3
A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE RECEPTORS. It contains a histone acetyltransferase activity that may play a role in CHROMATIN REMODELING during the process of nuclear receptor-induced transcription. The coactivator has been found at elevated levels in certain HORMONE-DEPENDENT NEOPLASMS such as those found in BREAST CANCER.
Year introduced: 2010(1997)
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Subheadings:
Tree Number(s): D08.811.913.050.134.415.500.150, D12.644.360.024.314.300, D12.776.157.057.080.300, D12.776.476.024.394.300, D12.776.660.675.300, D12.776.930.617.300
MeSH Unique ID: D056921
Registry Number: EC 2.3.1.48
Entry Terms:
- Nuclear Receptor Coactivator-3
- Receptor-Associated Coactivator 3
- Receptor Associated Coactivator 3
- Amplified in Breast Cancer-1 Protein
- Amplified in Breast Cancer 1 Protein
- Steroid Receptor Coactivator 3
- Thyroid Hormone Receptor Activator Molecule 1