Nuclear Receptor Co-Repressor 2

A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.

Year introduced: 2010(1995)

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Tree Number(s): D12.776.930.780.625.400

MeSH Unique ID: D056985

Entry Terms:

• Nuclear Receptor Co Repressor 2
• Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor
• T3 Receptor-associating Factor
• Receptor-associating Factor, T3
• T3 Receptor associating Factor
• SMRT Co-repressor
• Co-repressor, SMRT
• SMRT Co repressor
• TRAC Co-repressor
• Co-repressor, TRAC
• TRAC Co repressor

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
Repressor Proteins
Co-Repressor Proteins
Nuclear Receptor Co-Repressor 2