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Receptor Tyrosine Kinase-like Orphan Receptors

A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.

Year introduced: 2010

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Tree Number(s): D08.811.913.696.620.682.725.400.093, D12.776.476.568.400.093, D12.776.543.750.630.233

MeSH Unique ID: D057050

Registry Number: EC 2.7.10.1

Entry Terms:

  • Receptor Tyrosine Kinase like Orphan Receptors
  • Neurotrophic Tyrosine Kinase, Receptor-related Proteins
  • Neurotrophic Tyrosine Kinase, Receptor related Proteins
  • NTRKR Receptors
  • Receptor Tyrosine Kinase-like Orphan Receptor
  • Receptor Tyrosine Kinase like Orphan Receptor
  • ROR Tyrosine Kinase Receptors
  • Receptor Tyrosine Kinase-like Orphan Receptor 1
  • Receptor Tyrosine Kinase like Orphan Receptor 1
  • ROR1 Tyrosine Kinase
  • Tyrosine Kinase, ROR1
  • Receptor Tyrosine Kinase-like Orphan Receptor 2
  • Receptor Tyrosine Kinase like Orphan Receptor 2
  • ROR2 Tyrosine Kinase
  • Kinase, ROR2 Tyrosine

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