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Frontotemporal Lobar Degeneration

Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.

Year introduced: 2010

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Subheadings:

Tree Number(s): C10.228.140.380.266, C10.574.950.300, C18.452.845.800.300, F03.615.400.380

MeSH Unique ID: D057174

Entry Terms:

  • Degeneration, Frontotemporal Lobar
  • Degenerations, Frontotemporal Lobar
  • Frontotemporal Lobar Degenerations
  • Lobar Degeneration, Frontotemporal
  • Lobar Degenerations, Frontotemporal
  • FTLD
  • FTLDs

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