Nonsense Mediated mRNA Decay

An mRNA metabolic process that distinguishes a normal STOP CODON from a premature stop codon (NONSENSE CODON) and facilitates rapid degradation of aberrant mRNAs containing premature stop codons.

Year introduced: 2012

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Tree Number(s): G02.111.760.112, G02.111.780.500, G03.839.112, G05.308.700.112

MeSH Unique ID: D059365

Entry Terms:

• Nonsense-Mediated mRNA Decay
• Decay, Nonsense-Mediated mRNA
• mRNA Decay, Nonsense-Mediated

Previous Indexing:

• Codon, Nonsense (1999-2011)
• RNA, Messenger/metabolism (1994-2011)

See Also:

• RNA Cleavage

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
RNA Processing, Post-Transcriptional
Nonsense Mediated mRNA Decay

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
RNA Stability
Nonsense Mediated mRNA Decay

All MeSH Categories
Phenomena and Processes Category
Metabolism
RNA Processing, Post-Transcriptional
Nonsense Mediated mRNA Decay

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Gene Expression Regulation
RNA Processing, Post-Transcriptional
Nonsense Mediated mRNA Decay