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Telomere Shortening

The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.

Year introduced: 2012

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Subheadings:

Tree Number(s): G02.111.225.940, G04.043.630, G05.226.940, G07.345.124.130.630

MeSH Unique ID: D059506

Entry Terms:

  • Shortenings, Telomere
  • Shortening, Telomere
  • Telomere Shortenings

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