Endoplasmic Reticulum-Associated Degradation
A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.
Year introduced: 2012
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Subheadings:
Tree Number(s): G02.111.660.871.790.600.962.500, G02.111.691.600.850.500, G03.734.871.790.600.850.500, G04.434.500.500, G05.308.670.600.850.500
MeSH Unique ID: D060746
Entry Terms:
- Degradation, Endoplasmic Reticulum-Associated
- Endoplasmic Reticulum Associated Degradation
- Reticulum-Associated Degradation, Endoplasmic
- ERAD Pathway
- ERAD Pathways
- Pathway, ERAD
- Pathways, ERAD
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