B7-H1 Antigen
An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.
Year introduced: 2018 (2007)
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Tree Number(s): D12.776.465.625, D12.776.467.150.300, D12.776.543.095.300, D23.050.301.285.400, D23.529.168.300
MeSH Unique ID: D060890
Entry Terms:
- Antigen, B7-H1
- B7 H1 Antigen
- Programmed Death Ligand 1
- Antigens, CD274
- CD274 Antigens
- Programmed Cell Death 1 Ligand 1
- B7-H1 Immune Costimulatory Protein
- B7 H1 Immune Costimulatory Protein
- B7H1 Immune Costimulatory Protein
- PD-L1 Costimulatory Protein
- Costimulatory Protein, PD-L1
- PD L1 Costimulatory Protein
- Programmed Cell Death 1 Ligand 1 Protein
- PD-L1 Protein
- PD L1 Protein
- CD274 Antigen
- Antigen, CD274
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