Programmed Cell Death 1 Receptor

An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.

Year introduced: 2012

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Tree Number(s): D12.776.465.844, D12.776.543.750.705.222.875, D23.050.301.264.894.790, D23.101.100.894.790

MeSH Unique ID: D061026

Entry Terms:

• PD-1 Protein
• PD 1 Protein
• Programmed Cell Death 1 Protein
• Antigens, CD279
• CD279 Antigens
• CD279 Antigen
• Antigen, CD279
• PD1 Receptor
• Receptor, PD1
• Programmed Cell Death Protein 1
• PD-1 Receptor
• PD 1 Receptor
• Receptor, PD-1

Previous Indexing:

• Antigens, CD (1997-2011)
• Antigens, Surface (1997-2006)
• Apoptosis Regulatory Proteins (1977-2011)

See Also:

• Immunoglobulin Domains

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Immune Checkpoint Proteins
Programmed Cell Death 1 Receptor

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Receptors, Cell Surface
Receptors, Immunologic
Costimulatory and Inhibitory T-Cell Receptors
Programmed Cell Death 1 Receptor

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Antigens
Antigens, Surface
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
Programmed Cell Death 1 Receptor

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Biomarkers
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
Programmed Cell Death 1 Receptor