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Sialic Acid Binding Ig-like Lectin 3

A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE.

Year introduced: 2013

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Subheadings:

Tree Number(s): D12.776.503.921.400, D23.050.301.264.900.565, D23.101.100.900.565

MeSH Unique ID: D063268

Entry Terms:

  • Sialic Acid Binding Ig like Lectin 3
  • Antigens, CD33
  • CD33 Antigens
  • CD33 Antigen
  • Antigen, CD33
  • Glycoprotein gp67
  • gp67, Glycoprotein
  • Siglec-3

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