Solute Carrier Family 12, Member 1
Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE. Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME.
Year introduced: 2014
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Subheadings:
Tree Number(s): D12.776.157.530.450.625.875.750.500, D12.776.157.530.937.750.500, D12.776.543.585.450.625.750.500, D12.776.543.585.937.875.500
MeSH Unique ID: D064466
Entry Terms:
- Bumetanide-Sensitive Sodium-(Potassium)-Chloride Cotransporter 2
- Kidney-Specific Na-K-Cl Symporter
- Kidney Specific Na K Cl Symporter
- Na-K-Cl Symporter, Kidney-Specific
- Symporter, Kidney-Specific Na-K-Cl
- SLC12A1 Protein
- Protein, SLC12A1
- NKCC2 Protein
- Protein, NKCC2
- NKCC2 Cotransporter
- Cotransporter, NKCC2
- SLC12A1 Cotransporter
- Cotransporter, SLC12A1
- BSC1 Transport Protein
- Protein, BSC1 Transport
- Transport Protein, BSC1
See Also: