Protein Aggregation, Pathological

A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.

Year introduced: 2015

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Tree Number(s): C23.550.770, G02.111.675

MeSH Unique ID: D066263

Entry Terms:

• Aggregation, Pathological Protein
• Pathological Protein Aggregation

See Also:

• Protein Aggregates

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Diseases Category
Pathological Conditions, Signs and Symptoms
Pathologic Processes
Protein Aggregation, Pathological

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Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Protein Aggregation, Pathological