tau Proteins

Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).

Year introduced: 1992

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Tree Number(s): D12.776.220.600.450.510, D12.776.631.560.510

MeSH Unique ID: D016875

Entry Terms:

• Proteins, tau
• tau Protein
• Protein, tau

Previous Indexing:

• Microtubule-Associated Proteins (1986-1991)
• Microtubules (1976-1985)

See Also:

• Tauopathies

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Cytoskeletal Proteins
Microtubule Proteins
Microtubule-Associated Proteins
tau Proteins

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Nerve Tissue Proteins
Microtubule-Associated Proteins
tau Proteins