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Iridocorneal Endothelial Syndrome

A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.

Year introduced: 2010

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Tree Number(s): C11.204.497, C11.941.375.322

MeSH Unique ID: D057129

Entry Terms:

  • Endothelial Syndrome, Iridocorneal
  • Iridocorneal Endothelial Syndromes
  • ICE Syndrome
  • Chandler Syndrome
  • Iris Atrophy with Corneal Edema and Glaucoma
  • Chandler's Syndrome
  • Chandlers Syndrome

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