Hypomagnesemia primary [Supplementary Concept]
A progressive renal disorder characterized by excessive urinary Ca(2+) and Mg(2+) excretion. There is progressive loss of kidney function, and in about 50% of cases, the need for renal replacement therapy by the second decade of life. Germline mutations in the CLDN16 gene have been identified. OMIM: 603959
Date introduced: August 25, 2010
MeSH Unique ID: C537153
Heading Mapped to:
Entry Terms:
- Magnesium, defect in renal tubular transport of
- Hypomagnesemia, isolated renal
- Hypomagnesemia, familial, with hypercalciuria and nephrocalcinosis
- Hypomagnesemia 3, Renal
- Hypomagnesemia, Primary, Due To Defect In Renal Tubular Transport Of Magnesium