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Anti-Glomerular Basement Membrane Disease

An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.

Year introduced: 1998

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Tree Number(s): C08.381.483.156, C12.050.351.968.419.570.363.304, C12.200.777.419.570.363.304, C12.950.419.570.363.304, C20.111.190

MeSH Unique ID: D019867

Entry Terms:

  • Anti Glomerular Basement Membrane Disease
  • Anti-GBM Disease
  • Anti GBM Disease
  • Lung Purpura with Nephritis
  • Goodpasture's Syndrome
  • Goodpastures Syndrome
  • Syndrome, Goodpasture's
  • Goodpasture Syndrome
  • Syndrome, Goodpasture

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