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Familial medullary thyroid carcinoma [Supplementary Concept]

A malignant tumor of the CALCITONIN - secreting parafollicular C cells of the THYROID that occurs sporadically or as a component of the MULTIPLE ENDOCRINE NEOPLASIA (MEN) type 2 (OMIM: 171400)/familial medullary thyroid carcinoma (FMTC) syndromes. Germline mutations in the RET and NTRK1 genes have been identified. OMIM: 155240

Date introduced: August 25, 2010

MeSH Unique ID: C536911

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Entry Terms:

  • Thyroid cancer, familial medullary
  • Medullary thyroid cancer, familial
  • Thyroid Carcinoma, Familial Medullary

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