Familial medullary thyroid carcinoma [Supplementary Concept]
A malignant tumor of the CALCITONIN - secreting parafollicular C cells of the THYROID that occurs sporadically or as a component of the MULTIPLE ENDOCRINE NEOPLASIA (MEN) type 2 (OMIM: 171400)/familial medullary thyroid carcinoma (FMTC) syndromes. Germline mutations in the RET and NTRK1 genes have been identified. OMIM: 155240
Date introduced: August 25, 2010
MeSH Unique ID: C536911
Heading Mapped to:
Entry Terms:
- Thyroid Carcinoma, Familial Medullary
- Thyroid cancer, familial medullary
- Medullary thyroid cancer, familial