Chromosome 18 ring [Supplementary Concept]
Ring chromosome 18 arises when breaks occur at both ends of the chromosome, forming a circular structure. Affected individuals may have MICROCEPHALY; HYPERTELORISM; intellectual disability, and speech impairment. The severity of the disorders depends on how much genetic material is lost from the breaks.
Date introduced: August 25, 2010
MeSH Unique ID: C538304
Heading Mapped to:
Entry Terms:
- Ring Chromosome 18
- ring 18 chromosome syndrome