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Kleine-Levin Syndrome

A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569)

Year introduced: 1994

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Tree Number(s): C10.886.425.800.200.500, F03.870.400.800.200.500

MeSH Unique ID: D017593

Entry Terms:

  • Kleine Levin Syndrome
  • Syndrome, Kleine-Levin
  • Kleine-Levin Hibernation Syndrome
  • Hibernation Syndrome, Kleine-Levin
  • Kleine Levin Hibernation Syndrome
  • Syndrome, Kleine-Levin Hibernation
  • Kleine-Levin-Critchley Syndrome
  • Kleine Levin Critchley Syndrome
  • Syndrome, Kleine-Levin-Critchley
  • Hypersomnia, Periodic
  • Periodic Hypersomnia
  • Periodic Hypersomnias
  • Familial Kleine-Levin Syndrome
  • Familial Kleine Levin Syndrome
  • Kleine-Levin Syndrome, Familial
  • Syndrome, Familial Kleine-Levin
  • Familial Hibernation (Kleine-Levin) Syndrome

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