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Nelson Syndrome

A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.

Year introduced: 1991(1978)

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Tree Number(s): C04.588.322.609.145.500, C10.228.140.617.738.675.149.500, C19.344.609.145.500, C19.700.734.145.500

MeSH Unique ID: D009347

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