Thyroid cancer, medullary [Supplementary Concept]
A neuroendocrine carcinoma that originates in the C-cells of the THYROID GLAND; about 10-20% of cases are familial. It occurs sporadically or is associated with MULTIPLE ENDOCRINE NEOPLASIA SYNDROMES. Germline and somatic mutations in RET and NTRK1 genes have been identified. OMIM: 155240
Date introduced: August 25, 2010
MeSH Unique ID: C536914
Heading Mapped to:
Entry Terms:
- Medullary thyroid cancer (MTC)
- Thyroid carcinoma, medullary