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Thyroid cancer, medullary [Supplementary Concept]

A neuroendocrine carcinoma that originates in the C-cells of the THYROID GLAND; about 10-20% of cases are familial. It occurs sporadically or is associated with MULTIPLE ENDOCRINE NEOPLASIA SYNDROMES. Germline and somatic mutations in RET and NTRK1 genes have been identified. OMIM: 155240

Date introduced: August 25, 2010

MeSH Unique ID: C536914

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Entry Terms:

  • Thyroid carcinoma, medullary
  • Medullary thyroid cancer (MTC)

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