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Liddle Syndrome

Familial pseudoaldosteronism characterized by autosomal dominant inheritance of hypertension with HYPOKALEMIA; ALKALOSIS; RENIN and ALDOSTERONE level decreases. It is caused by mutations in EPITHELIAL SODIUM CHANNELS beta and gamma subunits. Different mutations in the same EPITHELIAL SODIUM CHANNELS subunits can cause PSEUDOHYPOALDOSTERONISM, TYPE I, AUTOSOMAL DOMINANT.

Year introduced: 2010

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Tree Number(s): C12.050.351.968.419.815.683, C12.200.777.419.815.683, C12.950.419.815.683, C16.320.831.698

MeSH Unique ID: D056929

Entry Terms:

  • Syndrome, Liddle
  • Pseudoaldosteronism

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