Noninsulin-dependent diabetes mellitus with deafness [Supplementary Concept]
A mitochondrial disorder characterized by onset of SENSORINEURAL HEARING LOSS and diabetes in adulthood. Some patients may have additional features observed in mitochondrial disorders, including RETINITIS PIGMENTOSA; PTOSIS; CARDIOMYOPATHY; MUSCULAR DISEASES; KIDNEY DISEASES, and neuropsychiatric symptoms. Mutations in the MITOCHONDRIAL GENES MTTL1, MTTE, and MTTK have been identified. OMIM: 520000
Date introduced: November 13, 2010
MeSH Unique ID: C536246
Heading Mapped to:
Entry Terms:
- Maternally inherited diabetes and deafness
- Diabetes-deafness syndrome, maternally transmitted
- Mitochondrial Inherited Diabetes and Deafness
- Ballinger-Wallace Syndrome
- Diabetes mellitus, type 2, with deafness
- NIDDM with deafness
- Maternally Transmitted Diabetes-Deafness Syndrome
- Diabetes Mellitus, Type II, With Deafness
- Diabetes and deafness, maternally inherited