MeSH

A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.

Year introduced: 1988

Substances that inhibit the growth or reproduction of BACTERIA.

Year introduced: 2004(1963)

Closely congeneric derivatives of the polycyclic naphthacenecarboxamide. (Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1117)

Year introduced: 1976

Aromatic hydrocarbons that contain extended fused-ring structures.

Year introduced: 2017(1996)

Compounds which contain two or more rings in their structure.

Year introduced: 2005(1974)

A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.

Year introduced: 1998

Polyacenes with four ortho-fused benzene rings in a straight linear arrangement. This group is best known for the subclass called TETRACYCLINES.

Year introduced: 1966

Organic compounds composed exclusively of carbon and hydrogen forming a closed ring that may be either alicyclic or aromatic.

Year introduced: 1998

Organic compounds containing carbon and hydrogen in the form of an unsaturated, usually hexagonal ring structure. The compounds can be single ring, or double, triple, or multiple fused rings.

Year introduced: 1998

Organic compounds that primarily contain carbon and hydrogen atoms with the carbon atoms forming a linear or circular structure.

Uses of chemicals which affect the course of conditions, diseases, syndromes or pathology to benefit the health of an individual.

Year introduced: 2004

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY.

Year introduced: 2008(2004)

A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.

Year introduced: 2004(1999)

A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.

Year introduced: 1999

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Year introduced: 1975(1964)

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.