MeSH Keyword for PubChem Compound (Select 991) - MeSH

Select item 680102781.

A highly toxic cholinesterase inhibitor that is used as an acaricide and as an insecticide.

Select item 680028002.

Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.

Year introduced: 1965

Select item 680073063.

Insecticides

Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.

Select item 680107554.

Organophosphates

Carbon-containing phosphoric acid derivatives. Included under this heading are compounds that have CARBON atoms bound to one or more OXYGEN atoms of the P(=O)(O)3 structure. Note that several specific classes of endogenous phosphorus-containing compounds such as NUCLEOTIDES; PHOSPHOLIPIDS; and PHOSPHOPROTEINS are listed elsewhere.

Year introduced: 2013(1975)

Select item 680099305.

Organic Chemicals

A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.

Year introduced: 1998

Select item 680099436.

Organophosphorus Compounds

Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.

Year introduced: 1972(1971)

Select item 680099467.

Organothiophosphorus Compounds

Compounds containing carbon-phosphorus bonds in which the phosphorus component is also bonded to one or more sulfur atoms. Many of these compounds function as CHOLINERGIC AGENTS and as INSECTICIDES.

Year introduced: 1972(1971)

Select item 680630868.

Organothiophosphates

Carbon-containing thiophosphoric acid derivatives. Included under this heading are compounds that have carbon bound to either SULFUR atom, or the OXYGEN atom of the SPO3 core structure.

Year introduced: 2013

Select item 680134579.

Sulfur Compounds

Inorganic or organic compounds that contain sulfur as an integral part of the molecule.

Year introduced: 1998

Select item 6801657310.

Agrochemicals

Chemicals used in agriculture. These include pesticides, fumigants, fertilizers, plant hormones, steroids, antibiotics, mycotoxins, etc.

Year introduced: 1992

Select item 6801837711.

Neurotransmitter Agents

Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.

Year introduced: 1998

Select item 6801057512.

Pesticides

Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.

Select item 6801867813.

Cholinergic Agents

Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage.

Year introduced: 1995

Select item 6802016414.

Chemical Actions and Uses

A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.

Year introduced: 1999

Select item 6802022815.

Pharmacologic Actions

A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.

Year introduced: 2004(1999)

Select item 6802031316.

Specialty Uses of Chemicals

Uses of chemicals in a research, industrial, or household setting. This does not include PHARMACOLOGIC ACTIONS.

Year introduced: 2004(1999)

Select item 6804550417.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY.

Year introduced: 2008(2004)

Select item 6800479118.

Enzyme Inhibitors

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Year introduced: 1975(1964)

Select item 6800478619.

Toxic Actions

A broad category of chemical actions with harmful or deadly effect on living organisms.

Year introduced: 2004(1998)

Select item 6804550520.

Physiological Effects of Drugs

Activities which affect organs and systemic functions without regard to a particular disease.