Homo sapiens DNA polymerase epsilon, catalytic subunit (POLE), RefSeqG - Nucleotide

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Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity. [Cancer Res Commun. 2024]
Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.
Shah SM, Demidova EV, Ringenbach S, Faezov B, Andrake M, Gandhi A, Mur P, Viana-Errasti J, Xiu J, Swensen J, et al. Cancer Res Commun. 2024 Jan 26; 4(1):213-225. Epub 2024 Jan 8.
The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway. [Cell Death Dis. 2024]
The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway.
Tang M, Yin S, Zeng H, Huang A, Huang Y, Hu Z, Shah AR, Zhang S, Li H, Chen G. Cell Death Dis. 2024 Jan 18; 15(1):69. Epub 2024 Jan 18.
Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer. [JAMA Netw Open. 2024]
Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer.
Zheng S, Donnelly ED, Strauss JB. JAMA Netw Open. 2024 Jan 2; 7(1):e2351906. Epub 2024 Jan 2.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the POLE gene.

Protein
Protein sequence from Nucleotide coding region
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TJP2 tight junction protein 2 [Homo sapiens]
TJP2 tight junction protein 2 [Homo sapiens]
Gene ID:9414

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Nucleotide