Homo sapiens sphingosine kinase 2 (SPHK2), transcript variant 4, mRNA

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YTHDF1-mediated sphingosine kinase 2 upregulation alleviates bupivacaine-induced neurotoxicity via the PI3K/AKT axis. [Hum Exp Toxicol. 2024]
YTHDF1-mediated sphingosine kinase 2 upregulation alleviates bupivacaine-induced neurotoxicity via the PI3K/AKT axis.
Yuan R, Wu C. Hum Exp Toxicol. 2024 Jan-Dec; 43:9603271231218707.
The accumulation of sphingosine kinase 2 disrupts the DNA damage response and promotes resistance to genotoxic agents. [Gene. 2024]
The accumulation of sphingosine kinase 2 disrupts the DNA damage response and promotes resistance to genotoxic agents.
da Silva G, Milan TM, Leopoldino AM. Gene. 2024 Mar 1; 897:148063. Epub 2023 Dec 2.
Accumulation of sphingosine kinase 2 protein induces malignant transformation in oral keratinocytes associated with stemness, autophagy, senescence, and proliferation. [Biochim Biophys Acta Mol Cell ...]
Accumulation of sphingosine kinase 2 protein induces malignant transformation in oral keratinocytes associated with stemness, autophagy, senescence, and proliferation.
Fugio LB, Silva G, Ferraz CL, Trevisan GL, Coeli-Lacchini FB, Garcia CB, Sousa LO, Malta TM, Gil CD, Leopoldino AM. Biochim Biophys Acta Mol Cell Res. 2024 Jan; 1871(1):119616. Epub 2023 Oct 28.

RefSeq alternative splicing
See 5 reference mRNA sequence splice variants for the SPHK2 gene.
RefSeq protein product
See the reference protein sequence for sphingosine kinase 2 isoform c (NP_001191089.1).

Protein
Protein sequence from Nucleotide coding region
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RecName: Full=Dual specificity protein phosphatase 12; AltName: Full=Dual specif...
RecName: Full=Dual specificity protein phosphatase 12; AltName: Full=Dual specificity tyrosine phosphatase YVH1
gi|9973073|sp|Q9UNI6.1|DUS12_HUMAN

Protein

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Nucleotide