Loss of α-actinin-3 during human evolution provides superior cold resilience and muscle heat generation.
Wyckelsma VL, Venckunas T, Houweling PJ, Schlittler M, Lauschke VM, Tiong CF, Wood HD, Ivarsson N, Paulauskas H, Eimantas N, et al. Am J Hum Genet. 2021 Mar 4; 108(3):446-457. Epub 2021 Feb 17.