Homo sapiens pellino E3 ubiquitin protein ligase family member 3 (PELI - Nucleotide

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Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation. [Exp Mol Med. 2023]
Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation.
Lee J, Ha J, Kim JH, Seo D, Kim M, Lee Y, Park SS, Choi D, Park JS, Lee YJ, et al. Exp Mol Med. 2023 Jun; 55(6):1218-1231. Epub 2023 Jun 1.
Pellino3 ligase negatively regulates influenza B dependent RIG-I signalling through downregulation of TRAF3-mediated induction of the transcription factor IRF3 and IFNβ production. [Immunology. 2023]
Pellino3 ligase negatively regulates influenza B dependent RIG-I signalling through downregulation of TRAF3-mediated induction of the transcription factor IRF3 and IFNβ production.
Kula A, Makuch E, Lisowska M, Reniewicz P, Lipiński T, Siednienko J. Immunology. 2023 Jul; 169(3):369-383. Epub 2023 Mar 14.
Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. [Nat Genet. 2021]
Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.
Ito T, Young MJ, Li R, Jain S, Wernitznig A, Krill-Burger JM, Lemke CT, Monducci D, Rodriguez DJ, Chang L, et al. Nat Genet. 2021 Dec; 53(12):1664-1672. Epub 2021 Dec 2.

RefSeq alternative splicing
See 8 reference mRNA sequence splice variants for the PELI3 gene.
RefSeq protein product
See the reference protein sequence for E3 ubiquitin-protein ligase pellino homolog 3 isoform 3 (NP_001230064.1).

Protein
Protein sequence from Nucleotide coding region
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Nucleotide