Homo sapiens ROS proto-oncogene 1, receptor tyrosine kinase (ROS1), tr - Nucleotide

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CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells. [FEBS J. 2024]
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
Xu X, Li Y, Xu R, Meng Y, Li Z, Zuo D, Wu Y. FEBS J. 2024 Mar; 291(6):1199-1219. Epub 2024 Jan 12.
Inflammatory Myofibroblastic Tumor With ROS1 Gene Fusions in Children and Young Adolescents. [JCO Precis Oncol. 2023]
Inflammatory Myofibroblastic Tumor With ROS1 Gene Fusions in Children and Young Adolescents.
Schoot RA, Orbach D, Minard Colin V, Alaggio R, Di Carlo D, Corradini N, Mercolini F, Milano GM, van Noesel MM, Rome A, et al. JCO Precis Oncol. 2023 Sep; 7:e2300323.
Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors. [EMBO Mol Med. 2023]
Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors.
Iyer SR, Nusser K, Jones K, Shinde P, Keddy C, Beach CZ, Aguero E, Force J, Shinde U, Davare MA. EMBO Mol Med. 2023 Oct 11; 15(10):e17367. Epub 2023 Aug 17.

RefSeq alternative splicing
See 31 reference mRNA sequence splice variants for the ROS1 gene.
RefSeq protein product
See the reference protein sequence for proto-oncogene tyrosine-protein kinase ROS isoform 1 precursor (NP_002935.2).

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c-ros oncogene 1, receptor tyrosine kinase [Guide to Pharmacology]
c-ros oncogene 1, receptor tyrosine kinase
Guide to Pharmacology
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Nucleotide