Homo sapiens methylenetetrahydrofolate dehydrogenase, cyclohydrolase a - Nucleotide

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma. [Cell Death Dis. 2024]
MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma.
Guan J, Li M, Wang Y, Zhang Y, Que Y, Lu S, Wang J, Zhu J, Huang J, Zhen Z, et al. Cell Death Dis. 2024 Feb 9; 15(2):124. Epub 2024 Feb 9.
Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. [Mol Cell. 2024]
Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel Ö, Beier V, von Gronau S, et al. Mol Cell. 2024 Jan 18; 84(2):293-308.e14. Epub 2023 Dec 18.
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability. [Cell. 2023]
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Gall-Duncan T, Luo J, Jurkovic CM, Fischer LA, Fujita K, Deshmukh AL, Harding RJ, Tran S, Mehkary M, Li V, et al. Cell. 2023 Oct 26; 186(22):4898-4919.e25. Epub 2023 Oct 11.

RefSeq alternative splicing
See the other reference mRNA sequence splice variant for the MTHFD1 gene (NM_001364837.1).
RefSeq protein product
See the reference protein sequence for C-1-tetrahydrofolate synthase, cytoplasmic isoform 1 (NP_005947.3).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
Probe
Related Probe entry
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Ensembl [Ensembl]
Ensembl
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
Order TALEN/CRISPR clone
GeneCopoeia Inc.
Order qPCR primer [GeneCopoeia Inc.]
Order qPCR primer
GeneCopoeia Inc.
Order full-length cDNA clone [GeneCopoeia Inc.]
Order full-length cDNA clone
GeneCopoeia Inc.
UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser

Homo sapiens methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formylt...
Homo sapiens methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1), transcript variant 1, mRNA
gi|1418483987|ref|NM_005956.4|

Nucleotide
CJ099743 RIKEN full-length enriched mouse cDNA library, C57BL/6J brain 14 days e...
CJ099743 RIKEN full-length enriched mouse cDNA library, C57BL/6J brain 14 days embryo Mus musculus cDNA clone M421009G24 5', mRNA sequence
gi|76200013|gnl|dbEST|31890893|dbj| 743.1|

Nucleotide
dynein axonemal heavy chain 12 isoform 2 [Homo sapiens]
dynein axonemal heavy chain 12 isoform 2 [Homo sapiens]
gi|89274173|ref|NP_940966.2|

Protein
Srf1p [Saccharomyces cerevisiae S288C]
Srf1p [Saccharomyces cerevisiae S288C]
gi|6320069|ref|NP_010149.1|

Protein

Your browsing activity is empty.

Activity recording is turned off.

Nucleotide