Homo sapiens iron-sulfur cluster assembly 2 (ISCA2), transcript varian - Nucleotide

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Copper exerts cytotoxicity through inhibition of iron-sulfur cluster biogenesis on ISCA1/ISCA2/ISCU assembly proteins. [Free Radic Biol Med. 2023]
Copper exerts cytotoxicity through inhibition of iron-sulfur cluster biogenesis on ISCA1/ISCA2/ISCU assembly proteins.
Du J, Huang Z, Li Y, Ren X, Zhou C, Liu R, Zhang P, Lei G, Lyu J, Li J, et al. Free Radic Biol Med. 2023 Aug 1; 204:359-373. Epub 2023 May 22.
ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma. [Oncogene. 2022]
ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma.
Green YS, Ferreira Dos Santos MC, Fuja DG, Reichert EC, Campos AR, Cowman SJ, Acuña Pilarte K, Kohan J, Tripp SR, Leibold EA, et al. Oncogene. 2022 Oct; 41(42):4709-4723. Epub 2022 Sep 12.
ISCA2 deficiency leads to heme synthesis defects and impaired erythroid differentiation in K562 cells by indirect ROS-mediated IRP1 activation. [Biochim Biophys Acta Mol Cell ...]
ISCA2 deficiency leads to heme synthesis defects and impaired erythroid differentiation in K562 cells by indirect ROS-mediated IRP1 activation.
Wang J, Jiang M, Yue G, Zhu L, Wang X, Liang M, Wu X, Li B, Pang Y, Tan G, et al. Biochim Biophys Acta Mol Cell Res. 2022 Oct; 1869(10):119307. Epub 2022 Jun 14.

RefSeq alternative splicing
See the other reference mRNA sequence splice variant for the ISCA2 gene (NM_001272007.2).
RefSeq protein product
See the reference protein sequence for iron-sulfur cluster assembly 2 homolog, mitochondrial isoform 1 precursor (NP_919255.2).

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Protein sequence from Nucleotide coding region
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Homo sapiens NKAT5-delta-Ig1/Ig2 mRNA, complete cds
Homo sapiens NKAT5-delta-Ig1/Ig2 mRNA, complete cds
gi|1217720|gb|L76667.1|HUMNKAT5DA

Nucleotide

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Nucleotide