PREDICTED: Homo sapiens DNA polymerase epsilon, catalytic subunit (POL - Nucleotide

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.

The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway. [Cell Death Dis. 2024]
The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway.
Tang M, Yin S, Zeng H, Huang A, Huang Y, Hu Z, Shah AR, Zhang S, Li H, Chen G. Cell Death Dis. 2024 Jan 18; 15(1):69. Epub 2024 Jan 18.
Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer. [JAMA Netw Open. 2024]
Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer.
Zheng S, Donnelly ED, Strauss JB. JAMA Netw Open. 2024 Jan 2; 7(1):e2351906. Epub 2024 Jan 2.
Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer. [In Vivo. 2024]
Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer.
Kitazono I, Akahane T, Yokoyama S, Kubota E, Nishida-Kirita Y, Noguchi H, Murakami M, Yanazume S, Kobayashi H, Tanimoto A. In Vivo. 2024 Jan-Feb; 38(1):321-333.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the POLE gene.
RefSeq protein product
See the reference protein sequence for DNA polymerase epsilon catalytic subunit A isoform X3 (XP_011533101.1).

Ensembl [Ensembl]
Ensembl
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone

RecName: Full=T-box transcription factor TBX10; Short=T-box protein 10
RecName: Full=T-box transcription factor TBX10; Short=T-box protein 10
gi|51338743|sp|O75333.2|TBX10_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Nucleotide