PREDICTED: Homo sapiens single Ig and TIR domain containing (SIGIRR), - Nucleotide

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IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC. [Semin Immunol. 2023]
IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC.
Mariotti FR, Supino D, Landolina N, Garlanda C, Mantovani A, Moretta L, Maggi E. Semin Immunol. 2023 Mar; 66:101712. Epub 2023 Feb 6.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation. [Nat Commun. 2022]
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation.
Wang L, Chen C, Song Z, Wang H, Ye M, Wang D, Kang W, Liu H, Qing G. Nat Commun. 2022 Jan 10; 13(1):12. Epub 2022 Jan 10.
SIGIRR Mutation in Human Necrotizing Enterocolitis (NEC) Disrupts STAT3-Dependent microRNA Expression in Neonatal Gut. [Cell Mol Gastroenterol Hepatol...]
SIGIRR Mutation in Human Necrotizing Enterocolitis (NEC) Disrupts STAT3-Dependent microRNA Expression in Neonatal Gut.
Yu W, Haque I, Venkatraman A, Menden HL, Mabry SM, Roy BC, Xia S, Prokop JW, Umar S, Geurts AM, et al. Cell Mol Gastroenterol Hepatol. 2022; 13(2):425-440. Epub 2021 Sep 23.

RefSeq alternative splicing
See 13 reference mRNA sequence splice variants for the SIGIRR gene.
RefSeq protein product
See the reference protein sequence for single Ig IL-1-related receptor isoform X2 (XP_047283343.1).

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